Relationship between body mass index and mortality in adults on maintenance hemodialysis: a systemic review*
SOURCE: Journal of Renal Nutrition
OUTPUT TYPE: Journal Article
PUBLICATION YEAR: 2010
TITLE AUTHOR(S): M.Herselman, N.Esau, J-M.Kruger, D.Labadarios, M.R.Moosa
KEYWORDS: ADULTS, BODY MASS INDEX (BMI), HEALTH, HEMODIALYSIS, MORTALITY
Print: HSRC Library: shelf number 6440
HANDLE: 20.500.11910/4174
URI: http://hdl.handle.net/20.500.11910/4174
OUTPUT TYPE: Journal Article
PUBLICATION YEAR: 2010
TITLE AUTHOR(S): M.Herselman, N.Esau, J-M.Kruger, D.Labadarios, M.R.Moosa
KEYWORDS: ADULTS, BODY MASS INDEX (BMI), HEALTH, HEMODIALYSIS, MORTALITY
Print: HSRC Library: shelf number 6440
HANDLE: 20.500.11910/4174
URI: http://hdl.handle.net/20.500.11910/4174
If you would like to obtain a copy of this Research Output, please contact Hanlie Baudin at researchoutputs@hsrc.ac.za.
Abstract
Objective: The primary objective of this systematic review was to determine the relationship between body mass index (BMI) and all-cause and cardiovascular mortality. Design: Systematic review of primarily observational studies. Patients: Adult patients from all gender, race, or ethnic groups on maintenance hemodialysis. Methods: Medline, Science Citation Index, Academic Search Premier, Cochrane Library, and Embase electronic databases covering the period 1966 to December 2008 were searched with the help of a qualified librarian. Reference lists of included papers and collections also were searched. Each study was reviewed by 2 independent reviewers who also performed the data extraction from full papers. Differences between reviewers were resolved by consensus or by a third reviewer in the case of disagreements. The quality of studies selected for inclusion in the systematic review was also assessed by 2 independent reviewers. Main Outcomes: BMI and mortality. Results: Eighteen studies (60%) reported a significant inverse relationship between all-cause mortality and BMI. This inverse relationship was more prevalent in older patients, larger retrospective studies, and studies that did not adjust for inflammation. On the other hand, 57% of the 7 studies reporting on cardiovascular mortality found no significant relationship with BMI. Conclusions: This systematic review shows evidence of an inverse relationship between BMI and all-cause mortality in adult patients on maintenance HD, especially in older patients, but the relationship with cardiovascular mortality is less clear.-
Related Research Outputs:
- Relationship between serum protein and mortality in adults on long-term hemodialysis: exhaustive review and meta-analysis
- Micronutrient supplementation for critically ill adults: a systemic review and meta-analysis
- Maternal and child undernutrition: consequences for adult health and human capital
- Tobacco use trends among adolescents and adults in South Africa
- Preliminary results of a population based study on global AGEing and adult health
- Ageing, health & chronic diseases in SA: preliminary results of a population based study on global AGEing and adult health
- Preliminary findings from a longitudinal cohort of individuals aged 50+: health risk behaviour and NCD prevalence
- Dietary, social, and environmental determinants of obesity in Kenyan women
- Characteristics and factors influencing fast food intake of young adult consumers in Johannesburg, South Africa
- Prevalence of obesity and associated factors in South Africans 50 years and older
- Study of global ageing and adult health (SAGE): South Africa 2007-2008: executive summary
- Tobacco use and associated factors in older adults in South Africa
- Physical inactivity and associated factors in older adults in South Africa
- Predictors of overweight and obesity in adult women in Nairobi province, Kenya
- Data resource profile: the World Health Organization study on global AGEing and adult health (SAGE)
- Self-rated health and associated factors among older South Africans: evidence from the study on global ageing and adult health
- Physical inactivity and associated factors in older adults in South Africa
- Study on global AGEing and adult health (SAGE), Wave 1: South Africa National Report
- Equity in maternal health in South Africa: analysis of health service access and health status in a national household survey
- Civil society activism in accessing healthcare in South Africa: technical report