Efficacy of an End-to-End Decentralized Service for PrEP in South Africa

STATUS: Current
PROJECT LEADER:Essack, Z (Dr )
OTHER TEAM MEMBERS: Joseph, PK (Mr Philip)
DEPARTMENT RESPONSIBLE: Public Health, Societies and Belonging (HSC)

Abstract

This is a randomized clinical study to test an end-to-end decentralized delivery service for PrEP. It aims to safely increase PrEP access and use among priority populations in South Africa. Participants will include 16-30 year old HIV negative women and sexual minority men at high risk for acquiring HIV. As a critical component of decentralized delivery, we will also evaluate the safety and efficacy of HIV self-testing compared to rapid diagnostic tests. The primary aim is to test an end-to-end decentralized delivery service for pre-exposure prophylaxis (PrEP) to safely increase PrEP access and use among priority populations in South Africa.